@Amolrs,
I agree with Andy's answer.
It seems commit changes will need datagrid to lose focus when you have a datatable. So if you need cell by cell edit, you may refer to here http://blog.scottlogic.com/2009/01/21/wpf-datagrid-committing-changes-cell-by-cell.html But checkbox seems not so easy in doing this.
Best regards,
Barry
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